Colorectal cancer screening: 20 years of development and recent progress

Progress and Challenges in Colorectal Cancer Screening

Although faecal and endoscopic tests appear to be effective in reducing colorectal cancer incidence and mortality, further technological and organizational advances are expected to improve the performance and acceptability of these tests. Several attempts to improve endoscopic technology have been made in order to improve the detection rate of neoplasia, especially in the proximal colon. Based ...

Colorectal cancer development and advances in screening

Most colon tumors develop via a multistep process involving a series of histological, morphological, and genetic changes that accumulate over time. This has allowed for screening and detection of early-stage precancerous polyps before they become cancerous in individuals at average risk for colorectal cancer (CRC), which may lead to substantial decreases in the incidence of CRC. Despite the kno...

Recent developments in colorectal cancer screening and prevention.

Colorectal cancer is a significant contributor to morbidity and mortality in the United States. Studies published in the early 1990s, showing that screening for colorectal cancer can reduce colorectal cancer-related mortality, led many organizations to recommend screening in asymptomatic, average-risk adults older than 50 years. Since then, however, national screening rates remain low. Several ...

Screening for Colorectal Cancer : Is There Progress for Early Detection ?

48 INTRODUCTION T he past decade experienced a great deal of debate about whether asymptomatic people should be screened for colorectal cancer. Fortunately, this debate largely is over and evidence-based guidelines now strongly recommend population-based screening for this major malignancy (1–3). Scientific and public discussion has shifted to the question of which of several screening strategi...

Is colorectal cancer screening necessary before 50 years of age?